Tumor Immunology: Immunotherapy and Cancer Vaccines (Cancer: Clinical Science in Practice)

Cambridge University Press, 11/24/2006
EAN 9780521159470, ISBN10: 0521159474

Paperback, 372 pages, 22.9 x 15.2 x 2 cm
Language: English

This 1996 volume reviewed advances in the field of human tumour immunology, particularly in relation to the potential for immune intervention in preventing or treating tumours. The editors and contributors, all prominent workers in the field, survey advances in the understanding of the relationship between the cancer cell and the immune response at the time of publication. Chapters review in depth the function of immune surveillance and mechanisms of tumour immunity, the role of T lymphocytes and oncogenes in the immune response to cancer, and the potential for immunotherapy of cancer. Areas of tumour immunology that were new at the time of this book's publication are presented, including progress in the development of tumour vaccines with particular reference to melanoma. The volumes in this series are intended for a wide audience of clinicians and researchers with an interest in the applications of biomedical science to the understanding and management of cancer.

Contributors
Series Editor's Preface
Abbreviations
1. Introduction and historical perspectives Michael Browning and A. G. Dalgleish
2. The immunosurveillance of cancer
specific and non-specific mechanisms Richard G. Vile, Heung Chong and Sina Dorudi
3. Antigen processing and presentation Nicholas C. Testifo and Michael Wang
4. The role of the MHC class I in tumor immunity Michael Browning
5. Human tumor antigens recognized by Cytolytic T Lymphocytes Pierre G Coulie
6. Peptide-specific CTL directed against viral oncogene products Mariet C.W. Feltkamp, Cornelis J. M. Melief and W. Martin Kast
7. Cellular oncogenes for tumor immunity
immunotherapy Hans J. Strauss and A. Maria Dahl
8. Co-stimulatory molecules and their role in tumour immunity A. G. Dalgleish
9. The role of cytokines in tumour rejection Guido Forni and Robin Foa
10. Inhibition of nonhemopoietic cancer cell growth by Interleukin-4 and related cytokines Dave S. B. Hoon, Takashi Morisaki and Richard Essner
11. Current concepts concerning melanoma vaccines Donald L. Morton and Mepur H. Ravindranath
12. Immune responses to mucins Rosalind A. Graham and Joyce Taylor-Papadimitriou
13. Heat shock protein-peptide complexes
pan-valent vaccines against cancers and infectious diseases Ryuichiro Suto and Pramod K. Srivastave
14. The potential of gene transfer to alter the immune response to tumors Bernard A. Fox and Gary J. Nabel
15. Applications of antibody gene technology Robert E. Hawkins and Kerry A. Chester
Index.