The Sperm Cell: Production, Maturation, Fertilization, Regeneration

Cambridge University Press, 4/6/2006
EAN 9780521853972, ISBN10: 0521853974

Hardcover, 372 pages, 24.6 x 17.5 x 2.3 cm
Language: English
Originally published in English

This is a comprehensive and definitive account of the human male gamete. The volume summarizes many unique and revealing characteristics of the sperm cell that have only recently been identified. It provides a detailed overview of human sperm production, maturation and function, and looks at how these processes affect and influence fertility, infertility and ART. This is the first dedicated account of the sperm cell to be published in almost a decade. The volume thus provides a very timely review of the most recent research and developments, augmented with the latest references. This book will appeal to all practitioners and scientists in reproductive medicine and in particular to clinical scientists, graduate and post-graduate scientists, and laboratory personnel.

1. Anatomical and compartmental analysis Peter Sutovsky and Gaurishankar Manandhar; 2. Sperm chromatin stability and susceptibility to damage in relation to its structure Jeffrey A. Shaman and W. Steven Ward; 3. Genomic and proteomic approaches to defining sperm production and function Sarah Conner, Linda Lefièvre and Christopher L. R. Barratt; 4. The epididymis and sperm maturation Trevor Cooper and C. H. Yeung; 5. Control of motility Claude Gagnon and Eve de Lamirande; 6. Regulation of capacitation Pablo Visconti and B. M. Gadella, 7. ROS's: friend or foe John Aitken and Liga Bennetts; 8. Testing sperm manufacturing quality: the sperm-zona binding assay Sergio Oehninger and Daniel Franken; 9. Genetics: a basic science perspective Peter Vogt; 10. Sex chromosome abnormalities and male infertility: a clinical perspective Shai Shefi and Paul J. Turek; 11. Epigenetic patterning in male germ cells: importance of DNA methylation to progeny outcome Jacquetta Trasler and Sophie La Salle; 12. The DAZ gene family and human germ cell development from embryonic stem cells Mark S. Fox, Renee A. Reijo Pera and Amander T. Clark; Index.

"The editors are to be congratulated on recruiting an outstanding list of contributors, many of whom are today's most active and productive investigators in their assigned topics... I wish a book like this had been available to me when I was in graduate school." Amy E.T. Sparks, Ph.D., New England Journal of Medicine "Overall, this book is an excellent overview of many aspects of sperm production and function. It will be very useful to researchers, andrologists and graduate students as well as those interested in gaining knowledge of what is known about spermatozoa." Mark Sigman, American Journal of Human Biology