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Case-Control Studies (Institute of Mathematical Statistics Monographs)

Case-Control Studies (Institute of Mathematical Statistics Monographs)

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Ruth H. Keogh, D. R. Cox
Cambridge University Press, 3/6/2014
EAN 9781107019560, ISBN10: 1107019567

Hardcover, 293 pages, 23.5 x 15.6 x 2 cm
Language: English

The case-control approach is a powerful method for investigating factors that may explain a particular event. It is extensively used in epidemiology to study disease incidence, one of the best-known examples being Bradford Hill and Doll's investigation of the possible connection between cigarette smoking and lung cancer. More recently, case-control studies have been increasingly used in other fields, including sociology and econometrics. With a particular focus on statistical analysis, this book is ideal for applied and theoretical statisticians wanting an up-to-date introduction to the field. It covers the fundamentals of case-control study design and analysis as well as more recent developments, including two-stage studies, case-only studies and methods for case-control sampling in time. The latter have important applications in large prospective cohorts which require case-control sampling designs to make efficient use of resources. More theoretical background is provided in an appendix for those new to the field.

Preface
Preamble
1. Introduction to case-control studies
2. The simplest situation
3. Matched case-control studies
4. A general formulation
5. Case-control studies with other than two outcomes
6. Special sampling designs
7. Nested case-control studies
8. Case-subcohort studies
9. Misclassification and measurement error
10. Synthesis of studies
Appendix. A theoretical diversion
References
Index.