Human Herpesviruses: Biology, Therapy, and Immunoprophylaxis

Cambridge University Press, 8/16/2007
EAN 9780521827140, ISBN10: 0521827140

Hardcover, 1408 pages, 28.4 x 23 x 6.3 cm
Language: English

This comprehensive account of the human herpesviruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, Epstein–Barr virus, Kaposi's Sarcoma-associated herpesvirus, cytomegalovirus, HHV6A, 6B and 7, and varicella-zoster virus. The viral diseases and cancers they cause are significant and often recurrent. Their prevalence in the developed world accounts for a major burden of disease, and as a result there is a great deal of research into the pathophysiology of infection and immunobiology. Another important area covered within this volume concerns antiviral therapy and the development of vaccines. All these aspects are covered in depth, both scientifically and in terms of clinical guidelines for patient care. The text is illustrated generously throughout and is fully referenced to the latest research and developments.

Part I. Introduction
Part II. Basic Virology and Viral Gene Effects on Host Cell Functions
Part II. Basic Virology and Viral Gene Effects on Host Cell Functions
Part II. Basic Virology and Viral Gene Effects on Host Cell Functions
Part III. Pathogenesis, Clinical Disease, Host Response, and Epidemiology
Part III. Pathogenesis, Clinical Disease, Host Response, and Epidemiology
Part III. Pathogenesis, Clinical Disease, Host Response, and Epidemiology
Part III. HHV- 6a, 6b and 7 Ann Arvin and Richard Whitley
Part III. Pathogenesis, Clinical Disease, Host Response, and Epidemiology
Part IV. Non-Human Primate Herpesviruses Ann Arvin, Patrick Moore and Richard Whitley
Part V. Subversion of Adaptive Immunity Richard Whitley and Ann Arvin
Part VI. Antiviral Therapy Richard Whitley
Part VII. Vaccines and Immunotherapy Ann Arvin and Koichi Yamanishi
Part VIII. Herpes as Therapeutic Agents Richard Whitley and Bernard Roizman.