Keynes & Aidley's Nerve and Muscle
Cambridge University Press
Edition: 5, 11/19/2020
EAN 9781108816878, ISBN10: 1108816878
Paperback, 324 pages, 24.1 x 18.4 x 2.5 cm
Language: English
Originally published in English
This well-established and acclaimed textbook introducing the rapidly growing field of nerve and muscle function has been completely revised and updated. Written with undergraduate students in mind, it begins with the fundamental principles demonstrated by the pioneering electrophysiological experiments on cell excitability. This leads to more challenging material recounting recent discoveries from applying modern biochemical, genetic, physiological and biophysical, experimental and mathematical analysis. The resulting interdisciplinary approach conveys a unified contemporary understanding of nerve and skeletal, cardiac and smooth muscle function at the molecular, cellular and systems levels. Emphasis on important strategic experiments throughout clarifies the basis for our current scientific views, highlights the excitement and challenge of biomedical discovery, and suggests directions for future advances. These fundamental ideas are then translated into discussions of related disease conditions and their clinical management. Now including colour illustrations, it is an invaluable text for students of physiology, neuroscience, cell biology and biophysics.
Preface
Acknowledgements
List of abbreviations
1. Structural organization of the nervous system
2. Resting and action potentials
3. Background ionic homeostasis of excitable cells
4. Membrane permeability changes during excitation
5. Voltage-gated ion channels
6. Cable theory and saltatory conduction
7. Neuromuscular transmission
8. Synaptic transmission in the nervous system
9. The mechanism of contraction in skeletal muscle
10. The activation of skeletal muscle
11. Excitation-contraction coupling in skeletal muscle
12. Contractile function in skeletal muscle
13. Cardiac muscle
14. Ion channel function and cardiac arrhythmogenesis
15. Smooth muscle
Further reading
References
Index.