Practical Psychopharmacology: Translating Findings From Evidence-Based Trials into Real-World Clinical Practice
Cambridge University Press
Edition: New, 6/17/2021
EAN 9781108450744, ISBN10: 1108450741
Paperback, 610 pages, 23.5 x 19 x 3.7 cm
Language: English
Originally published in English
Despite the lack of guidance available for practitioners, extensive polypharmacy has become the primary method of treating patients with severe and chronic mood, anxiety, psychotic or behavioral disorders. This ground-breaking new book provides an overview of psychopharmacology knowledge and decision-making strategies, integrating findings from evidence-based trials with real-world clinical presentations. It adopts the approach and mind-set of a clinical investigator and reveals how prescribers can practice 'bespoke psychopharmacology', tailoring care to the individualized needs of patients. Practitioners at all levels of expertise will enhance their ability to devise rationale-based treatments, targeting manifestations of dysfunctional neural circuitry and dimensions of psychopathology that cut across conventional psychiatric diagnoses. Presented in a user-friendly, practical, full-colour layout and incorporating summary tables, bullet points, and illustrative case vignettes, it is an invaluable guide for all healthcare professionals prescribing psychotropic medications, including psychiatry specialists, primary care physicians, and advanced practice registered nurses.
Part I. General Principles
1. Core concepts of good psychopharmacology
2. Targets of treatment
categories versus dimensions of psychopathology
3. Interpreting and using the literature
integrating evidence-based trials with real-world practice
4. Placebo and nocebo effects
5. Tailoring the fit
moderators and mediators of treatment outcome
6. Complex regimens and rationale-based combination drug therapies
7. Laboratory values and psychiatric symptoms
what to measure, what not to measure, and what to do with the results
8. Pharmacogenetics
when relevant, when not
9. Cross-tapering and the logistics of drug discontinuation
10. Managing major adverse drug effects
when to avoid, switch, or treat through
11. Novel drug therapeutics
nutraceuticals, steroids, probiotics, and other dietary supplements
12. Human diversity and considerations in special populations
Part II. Targets of Pharmacotherapy
13. Disordered mood and affect
14. Disorders of impulsivity, compulsivity, and aggression
15. Psychosis
16. Deficit states and negative symptoms
17. Anxiety
18. Addiction and the reward pathway
19. Trauma and posttraumatic stress disorder
20. Personality disorders
21. Cognition
22. Putting it all together
References
Index.