Brain Control of Responses to Trauma

Cambridge University Press, 9/15/1994
EAN 9780521419390, ISBN10: 0521419395

Hardcover, 354 pages, 22.9 x 15.2 x 2.3 cm
Language: English

Originally published in 1994, this was the first volume to look in depth at the way the brain responds to trauma and subsequently integrates and influences behavioural, metabolic, neurohumoral, cardiovascular and immune functions. At the time, the role of the brain in the control and integration of the responses to injury and infection was becoming increasingly clear. It had been established that some of these responses, such as fever and neuroendocrine changes, responded to the direct influence of the central nervous system. These, and other advances, provided fresh insights into this area and formed a basis for the more effective understanding and clinical management of trauma patients. In this volume, the authors, all international authorities in their fields, discuss data from experimental and clinical studies and considered the implications of these findings for the treatment of the trauma patient.

1. Introduction N. J. Rothwell
2. Overview of responses to injury B. Stonar
3. Experimental approaches to the study of CNS control of responses to injury N. J. Rothwell and R. Little
4. CNS control and neural mediations of immune responses and inflammation D. Payan
5. Neurohormonal control of cytokines during injury I. Berczi
6. Brain regions involved in modulation of immune responses P. Neveu
7. Psychological and neurobiological consequences of trauma C. Nemeroff
8. CNS control of sickness behaviour Robert Dantzer
9. Psychological and behavioural aspects of pain H. Ursin
10. Central control of cardiovascular responses to injury R. Little and E. Kirkman
11. Endocrine/neuroendocrine responses to trauma F. Berkenbosch
12. Central control of the metabolic and thermoregulatory responses to injury N. J. Rothwell
13. Central control of pain R. W. Clarke
Index.

"This is a notable contribution, of wider potential clinical interest than might appear, since virtually all types of bodily insult or damage rather than 'trauma' in the sense only of injury, are brought into the same integrative perspective." Sheila Jennett, Journal of the Royal Society of Medicine "...an interesting approach to the primarily chemical study of cerebral tissue responses to trauma." Electroencephalography and Clinical Neurophysiology