Disorders of Neuronal Migration (International Review of Child Neurology (Mac Keith Press))
MacKeith Press, 17/07/2003
EAN 9781898683315, ISBN10: 189868331X
Hardcover, 220 pages, 23.1 x 15.7 x 2 cm
Neuronal migration is a unique process during the development of brain structure. Although cerebral anomalies resulting from impaired migration have been identified for nearly a century, most of our knowledge has accumulated in the last decade. Disorders of neuronal migration are causes of mental handicap, autism, and epilepsy. Many are genetically determined and need precise diagnosis to provide genetic counselling. This book addresses the various aspects of neuronal migration disorders in an ordered way. It will help the clinician to acquire insight as well as proficiency in diagnosis. Individual chapters describe subgroups including lissencephalies, subependymal heterotopia, non-lissencephalic cortical dysplasias, anomalies of the corpus callosum, hemimegalencephaly, schizencephaly, polymicrogyria and multisystem disorders with impaired migration such as chromosomal and metabolic syndromes. Neuroradiological and genetic data are provided with the respective chapters. Although the book is intended for clinical practice, it provides core information for all interested in this important biological process.
"I found this to be a very worthwhile book which provides an excellent overview of a challenging and increasingly important area of pediatric neurology." Developmental Medicine & Child Neurology
"This book is going to be a text of reference for neurologists and epileptologists no mater how many updated classifications of malformations of cortical development may arise." Infant & Child Development