Mechanics of Biomaterials: Fundamental Principles for Implant Design (Cambridge Texts in Biomedical Engineering)

Mechanics of Biomaterials: Fundamental Principles for Implant Design (Cambridge Texts in Biomedical Engineering)

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Lisa A. Pruitt, Ayyana M. Chakravartula
Cambridge University Press, 10/20/2011
EAN 9780521762212, ISBN10: 0521762219

Hardcover, 698 pages, 25.4 x 20.3 x 3.8 cm
Language: English

Teaching mechanical and structural biomaterials concepts for successful medical implant design, this self-contained text provides a complete grounding for students and newcomers to the field. Split into three sections: Materials, Mechanics and Case Studies, it begins with a review of sterilization, biocompatibility and foreign body response before presenting the fundamental structures of synthetic biomaterials and natural tissues. Mechanical behavior of materials is then discussed in depth, covering elastic deformation, viscoelasticity and time-dependent behavior, multiaxial loading and complex stress states, yielding and failure theories, and fracture mechanics. The final section on clinical aspects of medical devices provides crucial information on FDA regulatory issues and presents case studies in four key clinical areas: orthopedics, cardiovascular devices, dentistry and soft tissue implants. Each chapter ends with a list of topical questions, making this an ideal course textbook for senior undergraduate and graduate students, and also a self-study tool for engineers, scientists and clinicians.

Part I. Materials
1. Biocompatibility, sterilization and materials selection for implant design
2. Metals for medical implants
3. Ceramics
4. Polymers
5. Mechanical behavior of structural tissues
Part II. Mechanics
6. Elasticity
7. Viscoelasticity
8. Failure theories
9. Fracture mechanics
10. Fatigue
11. Friction, lubrication and wear
Part III. Case Studies
12. Regulatory affairs and testing
13. Orthopedics
14. Cardiovascular devices
15. Oral and maxillofacial devices
16. Soft tissue replacements
Appendix A. Selected topics from mechanics of materials
Appendix B. Table of material properties of engineering biomaterials and tissues
Appendix C. Teaching methodologies in biomaterials
List of symbols.

Advance praise: 'Mechanics of Biomaterials is the textbook I have been waiting for. This comprehensive work synthesizes the science and engineering of biomaterials that has developed over the past three decades into a highly useful textbook for training students ... as I reviewed this work it felt like I was reviewing my own lecture notes developed over 20 years. [It] combines materials science, mechanics and medical device design and analysis in a seamless and thorough manner incorporating many critical studies from the literature into a clear and comprehensive work ... Pruitt and Chakravartula have succeeded in developing an outstanding text and reference book that should be required reading for all who aspire to design, develop and evaluate medical devices.' Jeremy L. Gilbert, Syracuse University