Neurocognitive Rehabilitation of Down Syndrome (Cambridge Medicine (Paperback))
Cambridge University Press, 6/2/2011
EAN 9781107400436, ISBN10: 1107400430
Paperback, 252 pages, 23.4 x 15.6 x 1.3 cm
Language: English
Down syndrome is one of the most commonly occurring developmental disorders and it is now possible to conceptualize and define opportunities for neurocognitive rehabilitation for those with the condition. This book describes how early cognitive intervention in children with Down syndrome can be carried out, and can reduce, or compensate for, the major deficits characteristic of the condition. This comprehensive account relates the neurocognitive approach to the major therapeutic endeavors in the neighboring fields of neurogenetics, experimental environmental enrichment, molecular genetics, pharmacology, pediatrics and cardiology for infants with Down syndrome. Neurocognitive Rehabilitation of Down Syndrome provides the guidance required to establish effective rehabilitation programs, and is essential reading for developmental clinicians, pediatricians, neuropsychologists and other health professionals.
Preface
Part I. Definition, History, Methodology, and Assessment
1. Early intervention
definition, objectives, models and challenges Juan Perera
2. The history of rehabilitative intervention for infants and young children with Down syndrome and their families
where have we been and where are we going? Donna Spiker
3. Advances in clinical endpoints for neurocognitive rehabilitation in Down syndrome Jamie Edgin, Goffredina Spano and Lynne Nadel
Part II. Genetics, Brain and Animal Models
4. New perspectives on molecular and genetic therapies in Down syndrome Jean-Maurice Delabar
5. Brain plasticity and environmental enrichment in Ts65Dn mice, an animal model for Down syndrome Adam Golabek, Katarzyna JarzÄ…bek, Sonia Palminiello, Marius Walus, Ausma Rabe, Giorgio Albertini and Elizabeth Kida
6. Development of the brain and metabolism David Patterson
Part III. Pharmacological and Medical Management and Treatment
7. Pharmacotherapy for children with Down syndrome George Capone
8. Early medical caretaking and follow-up Alberto Rasore-Quartino
9. Evaluation and management of cardiovascular diseases in Down syndrome Guy Dembour and Stephane Moniotte
Part IV. Early Development and Intervention
10. Developmental models as frameworks for early intervention with children with Down syndrome Katie Cohene, Heidi Flores and Jacob Burack
11. Aspects of motor development in Down syndrome Naznin Virji-Babul, Anne Jobling, Digby Elliot and Daniel Weeks
12. Memory development and learning Stefano Vicari and Deny Menghini
13. Prelinguistic and early development, stimulation and training in children with Down syndrome Jean-Adolphe Rondal
14. Speech perception, stimulation and phonological development Michele Pettinato
15. Goal-directedness as a target for early intervention in Down syndrome Deborah Fidler, Susan L. Hepburn and Diane Osaki
16. The role of parents of children with Down syndrome and other disabilities in early intervention Gerald Mahoney and Frida Perales
Part V. Therapeutic Perspectives
17. Perspectives of hybrid therapeutic strategies in intellectual disabilities and Down syndrome Jean-Adolphe Rondal and Juan Perera
Conclusions
Index.